PRP Facial Rejuvenation

Platelet Rich Plasma (PRP) has been used in facial rejuvenation around the world since 2006. The treatment is ideal for individuals looking for gradual but noticeable improvement in skin texture, tone, and color with minimal or no recovery time. This revolutionary natural procedure offers incredible skin rejuvenation. Platelets in your blood contain numerous Platelet Derived Growth Factors (PDGF). These growth factors stimulate proliferation of fibroblasts and keratinocytes, which produce collagen and keratin. PDGF have a significant role in blood vessel formation, the cellular division of fibroblasts (the most common cells in connective tissue), and in synthesizing collagen and the extracellular matrix, including hyaluronic acid. Collagen production has been attributed to helping correct the visible effects of wrinkles. Hyaluronic acid has been shown to increase skin tone and volume providing a more youthful appearance.
This procedure is not a surgical face lift nor does it create the same effect as a face lift. The procedure helps restore or enhance areas, which require volume. Improvement of skin texture and tone can be noticeable within three weeks and improvement continues for the next 8 months as more collagen and keratin is laid under the skin. The results typically last 2 years or longer. Areas of treatment include cheeks and mid-face, wrinkling around the eyes, smile lines, nasolabial fold, neck and jawline, chest, acne scarring, hands, and more. The process takes between 60-90 minutes, depending on complexity. For the best result, we recommend three to six treatments, 4-6 weeks apart.

The Physiologic Fundamentals of PRP

Mesenchymal Stem cells
Scientists have known for years that unipotent cells lie dormant in the skin and provide the building blocks for healing when you sustain a burn or cut. Until recently, physicians had no convenient way to stimulate those stem cells to grow new tissue. By utilizing the growth factors found in the blood (specifically the platelets), but now they have found an approach to activate the unipotent stem cells already in the skin and tell those cells to grow new, younger-appearing skin. During the process of the PRP facial rejunivation, stem cell science is used to tell the body to grow new younger skin. Unipotent stem cells, which grow only one specific tissue, and can be found in every part of the body. For example, unipotent stem cells in the liver grow new liver tissue. Unipotent stem cells in the skin grow new skin.

What happens during a facial rejuvenation treatment with PRP?

Creating a Beautiful & Natural Shape
  • In the first part of the procedure, the physician uses a Hyaluronic Acid (HA) filler (like Restylane or Juvederm) in a very specific way to sculpt a younger appearing face–while still keeping the shape natural. Your doctor takes into account the mathematics of beauty as defined by much research (starting with the notebooks of Lonardo da Vinci) to avoid at all costs creating an unnatural shape.

  • Second, the physician draws a similar amount of blood normally required for a basic blood test.

Isolating & Activating the Growth Factors from Your Blood
  • Then, using a centrifuge (Figure 1), the physician isolates platelets from that blood (platelet-rich plasma or PRP)–all within about 10 minutes in the office.

  • Then he “activates” those platelets to cause the release from the platelets of at least 8 growth factors that would normally be used to heal injured tissue. These growth factors work like magic to cause increased collagen & new blood flow. To rejuvenate new skin, these growth factors must be put back into your face.

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Figure 1 Centrifuge

Injecting the Growth Factors into Your Face
  • Using numbing cream and a very small needle (for almost no pain), the physician injects your own growth factors back into your face (Figure 2) in a particular way. These growth factors then activate multipotent stem cells already in the skin (tricking them into “thinking” there’s been an injury and new younger tissue should be generated).

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Figure 2 Growth Factors injection

The multipotent stem cells then develop into new collagen, new blood vessels, and new fatty tissue trying to “repair” the skin that was never injured!

Is the procedure painful?

Numbing cream is applied to the face 45 minutes before the procedure, making the treatment very comfortable. Most patients do not feel much sensation.

How long is the recovery time?

Typically, there is little to no downtime associated with the treatment. Some redness of the treated area may last a day after treatment. Minor bruising may occur, but clears up in about a week and can be concealed with cosmetics. Normal activity can be resumed immediately, but your face should be protected from the sun.

How long is the treatment?

On the treatment day, the entire visit lasts about 2 hours. The actual procedure requires about 20 minutes.

Is it safe?

PRP treatment is extremely safe. Because PRP is produced from your own blood, there is no risk of an allergic reaction. In addition, PRP contains concentrated amount of white blood cells, your natural defenders against infections. As a result, infection is extremely rare with our PRP treatment.

Are there any contraindications?

Persons with active skin infections, acne, skin disease (SLE, porphyria, allergies), cancer, chemotherapy, severe metabolic and systemic disorders, abnormal platelet function (i.e. blood disorders), and underlying sepsis excludes the use of PRP.

How many treatments are needed?

Initially, 3 to 6 treatments 4-6 weeks apart are recommended for optimal results. Thereafter, maintenance treatments are recommended every one to two years depending on skin type.